This paper discusses the role of ICTs in poverty reduction. It is organised into three sections. The first section focuses on poverty in Asia, highlighting the important distinction between ‘development’ and ‘poverty reduction’. The second section focuses on issues surrounding the application of ICTs for poverty reduction, including the importance of focusing on information and communication needs rather than on technology, comparison of the different strengths and weaknesses of various ICTs, access and outreach, economic and social impact, the importance of multi-sector partnerships, etc. The third section presents several ICT for Poverty Reduction case studies, describing the particular application of ICT and discusses targeting the poor, outreach, expandability/replicability, and sustainability.